Healing the Future

This brief documents the process and findings of a horizon scanning exercise, in the context of FUTURINNOV (FUTURe-oriented detection and assessment of emerging technologies and break-through INNOVation) a collaboration between the European Innovation Council (EIC) and the Joint Research Centre (JRC), aiming to support the EIC's strategic intelligence through foresight and other anticipatory methodologies.

The workshop, held online on 15 May 2025, had as its primary goal the evaluation and prioritisation of trends and signals related to emerging technologies and breakthrough innovation, across all technology readiness levels (TRLs), within cell and gene therapies.

Signals for the workshop were gathered from experts, literature review, and text/data mining of patents, publications, and EU-funded projects. These signals were then scrutinised for their significance to the field's future by a diverse group of sector experts, which led to the identification of seven key topics: in vivo gene therapy; microphysiological pre-clinical models; stem cells in multiple applications; new tools for advanced tissue delivery; in silico & AI; conversion of tumour cells; and emerging genome and epigenome-based therapies.

Participants also highlighted various contextual factors that could influence the development, adoption, and uptake of emerging technologies within this field, including in domains such as: competitiveness and geopolitics; talent and expertise; cross-border and cross-sector collaboration; funding, economic and market conditions; regulatory, safety and ethical challenges; health and RDI ecosystems; and infrastructure and manufacturing.